The implications of drought and water conservation on the reuse of municipal wastewater: Recognizing impacts and identifying mitigation possibilities illustrates how drought and water conservation strategies, such as water reuse, can lead to a reduction in effluent quantity and quality. The report demonstrates that as influent decreases as a result of drought and water conservation strategies, influent pollution concentrations (especially salinity) and wastewater treatment plant costs increase, ultimately leading to a decrease in effluent quality and flow. The report includes a case study of Southern California’s most recent drought and a water reuse decision support model (RWRM) to mitigate drought impacts on water quality.